IHC of PAX-2 on an FFPE Kidney Tissue

IHC of PAX-2 on an FFPE Kidney Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use.
Summary and Explanation PAX-2 is a homeogene strongly expressed during kidney development. PAX-2 gene is expressed in the metanephric mesenchyma after ureter bud induction and is a key factor for the mesenchyma-epithelium conversion. Animals transgenic for PAX-2 have severe renal abnormalities and cysts but no solid tumoral features.Anti-PAX-2 can be used to distinguish Ovarian Serous Papillary Carcinoma (PAX-2 positive) from Primary Breast Carcinoma (PAX-2 negative). It can also be used to distinguish Clear Cell Renal Carcinoma (positive) from Hepatocellular Carcinoma
(negative).
Antibody Type Rabbit Monoclonal Clone EP235
Isotype IgG Reactivity Paraffin, Frozen
Localization Nuclear Control Kidney, Fallopian Tube, Clear Cell Renal Carcinoma, Ovarian Serous Papillary Carcinoma
Presentation PAX-2 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 2566 Prediluted Ready-To-Use 3.0 ml
BSB 2567 Prediluted Ready-To-Use 7.0 ml
BSB 2568 Prediluted Ready-To-Use 15.0 ml
BSB 2569 Concentrated 1:50-1:200 0.1 ml
BSB 2570 Concentrated 1:50-1:200 0.5 ml
BSB 2571 Concentrated 1:50-1:200 1.0 ml
BSB 2572 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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