IHC of Napsin on an FFPE Lung Adenocarcinoma Tissue

IHC of Napsin on an FFPE Lung Adenocarcinoma Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation The activation peptides of aspartic proteinases play a role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A gene is expressed predominantly in lung and kidney. Its translation product is predicted to be a fully functional glycosylated aspartic proteinase precursor containg an RGD motif and an addition 18 residues at its C-terminus.
In normal tissue, anti-Napsin A labels type II pneumocytes in adult lung and epithelial cells in kidney tissues. In abnormal tissues, Napsin A is a useful marker for lung adenocarcinoma.
Antibody Type Rabbit Monoclonal Clone EP205
Isotype IgG Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Kidney, Lung, Lung Carcinoma, Renal Cell Carcinoma
Presentation Napsin A is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 6988 Prediluted Ready-To-Use 3.0 ml
BSB 6989 Prediluted Ready-To-Use 7.0 ml
BSB 6990 Prediluted Ready-To-Use 15.0 ml
BSB 6991 Concentrated 1:10-1:50 0.1 ml
BSB 6992 Concentrated 1:10-1:50 0.5 ml
BSB 6993 Concentrated 1:10-1:50 1.0 ml
BSB 6994 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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