IHC of Napsin A on a FFPE Lung Carcinoma Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation

The activation peptides of aspartic proteinases play a role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A gene is expressed predominantly in lung and kidney. Its translation product is predicted to be a fully functional glycosylated aspartic proteinase precursor containg an RGD motif and an addition 18 residues at its C-terminus.

In normal tissue, anti-Napsin A labels type II pneumocytes in adult lung and epithelial cells in kidney tissues. In abnormal tissues, Napsin A is a useful marker for lung adenocarcinoma.

Antibody Type Mouse Monoclonal Clone BSB-112
Isotype IgG1/K Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Kidney, Lung, Renal Cell Carcinoma, Lung Carcinoma
Presentation Napsin A is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 3392 Prediluted Ready-To-Use 3.0 ml
BSB 3393 Prediluted Ready-To-Use 7.0 ml
BSB 3394 Prediluted Ready-To-Use 15.0 ml
BSB 3395 Concentrated 1:100-1:500 0.1 ml
BSB 3396 Concentrated 1:100-1:500 0.5 ml
BSB 3397 Concentrated 1:100-1:500 1.0 ml
BSB 3398 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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