IHC of Myeloperoxidase on an FFPE Bone Marrow Tissue

Specification Sheets
Safety Data Sheet


Intended Use For In Vitro Diagnostic Use
Summary and Explanation Myeloperoxidase (MPO) is a peroxidase enzyme most abundantly present in neutrophil granulocytes. It is a lysosomal protein stored in azurophilic granules of the neutrophil. MPO has a heme pigment, which causes its green color in secretions rich in neutrophils, such as pus and some forms of mucus. Historically, immunohistochemical staining for myeloperoxidase was used in the diagnosis of Acute Myeloid Leukemia to demonstrate that the leukemic cells were derived from the myeloid lineage. Myeloperoxidase staining is still important in the diagnosis of Extramedullary Leukemia or Chloroma.
Myeloperoxidase detects granulocytes and monocytes in blood and precursors of granulocytes in the bone marrow. This antibody can detect myeloid cell populations of the bone marrow as well as in other sites.
Antibody Type Rabbit Monoclonal Clone EP151
Isotype IgG Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Bone Marrow
Presentation Myeloperoxidase is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No. Antibody Type Dilution Volume/QTY
BSB 6967 Prediluted Ready-To-Use 3.0 ml
BSB 6968 Prediluted Ready-To-Use 7.0 ml
BSB 6969 Prediluted Ready-To-Use 15.0 ml
BSB 6970 Concentrated 1:250-1:1000 0.1 ml
BSB 6971 Concentrated 1:250-1:1000 0.5 ml
BSB 6972 Concentrated 1:250-1:1000 1.0 ml
BSB 6973 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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