IHC of MUM1 on an FFPE Kidney Tissue

IHC of MUM1 on an FFPE Kidney Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation MUM1 (multiple myeloma oncogene-1) also known as interferon regulatory factor 4 (IRF4) is a 50 kDa protein and is a member of the interferon regulatory factor family of transcription factors. It is induced by antigen receptor mediated stimuli and plays an important role in cell proliferation, differentation and survival. MUM1 is expressed in the nuclei and cytoplasm of plasma cells and a small percentage of germinal center (GC) B-cells commited to plasmacytic or memory cell differentation in the “light zone”.
MUM1 is useful for subclassification of lymphoid malignancies and is an excellent marker for Hodgkin’s and Reed-Sternberg cells of classic Hodgin’s disease.
Antibody Type Rabbit Monoclonal Clone EP190
Isotype IgG Reactivity Paraffin, Frozen
Localization Cytoplasmic, Nuclear Control Tonsil, Lymph Node, Plasmacytoma, Hodgkin’s Lymphoma
Presentation MUM1 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 6953 Prediluted Ready-To-Use 3.0 ml
BSB 6954 Prediluted Ready-To-Use 7.0 ml
BSB 6955 Prediluted Ready-To-Use 15.0 ml
BSB 6956 Concentrated 1:25-1:100 0.1 ml
BSB 6957 Concentrated 1:25-1:100 0.5 ml
BSB 6958 Concentrated 1:25-1:100 1.0 ml
BSB 6959 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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