IHC of Melanoma/PNL2 on an FFPE Melanoma Tissue

IHC of Melanoma / PNL2 on an FFPE Melanoma Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation PNL2 is a mouse monoclonal antibody that reacts against an antigen present in melanocytic tumors such as Melanomas. The antibody was generated to an extract of Melanoma. It reacted positively against Melanocytic Tumors but not other tumors, thus demonstrating specificity and sensitivity. Moreover, this antibody reacts positively against junctional nevus cells but not intradermal nevi, and against fetal melanocytes but not normal adult melanocytes.
This antibody is very useful to identify Malignant Melanoma. Metastatic Amelanotic Melanoma can often be confused with a variety of poorly differentiated Carcinomas, Large Cell Lymphomas, Sarcomas, Spindle Cell Carcinomas and various types of mesenchymal neoplasms. A keratin-negative, vimentin-rich neoplasm that immunoreacts with antibody to S-100 protein and with this melanoma antibody, is, with rare exception, a Melanoma.
Antibody Type Mouse Monoclonal Clone PNL2
Isotype IgG1 Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Melanoma
Presentation Melanoma/PNL2 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 6912 Prediluted Ready-To-Use 3.0 ml
BSB 6913 Prediluted Ready-To-Use 7.0 ml
BSB 6914 Prediluted Ready-To-Use 15.0 ml
BSB 6915 Concentrated 1:100-1:500 0.1 ml
BSB 6916 Concentrated 1:100-1:500 0.5 ml
BSB 6917 Concentrated 1:100-1:500 1.0 ml
BSB 6918 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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