IHC of Lambda on an FFPE Tonsil Tissue

IHC of Lambda on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Lambda detects surface immunoglobulin on normal and neoplastic B-cells. Lambda staining is seen in B-cell follicles of human lymphoid tissue. When studying B-cell neoplasms, the determination of light chain ratios remains the centerpiece. This is sound reasoning because most B-cell Lymphomas express either kappa or lambda light chains, whereas reactive proliferations display a mixture of kappa and lambda-positive cells. If only a single light-chain type is detected, a lymphoproliferative disorder is very likely. Monoclonality is determined by a kappa-lambda ratio greater than or equal to 3:1, a lambda-kappa ratio greater than or equal to 2:1, or a monoclonal population of 75% or moreof the total population.
Antibody Type Mouse Monoclonal Clone BSB-16
Isotype IgG2a Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Tonsil, Lymph Node
Presentation Lambda antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 5715 Prediluted Ready-To-Use 3.0 ml
BSB 5716 Prediluted Ready-To-Use 7.0 ml
BSB 5717 Prediluted Ready-To-Use 15.0 ml
BSB 5718 Concentrated 1:250-1:1000 0.1 ml
BSB 5719 Concentrated 1:250-1:1000 0.5 ml
BSB 5720 Concentrated 1:250-1:1000 1.0 ml
BSB 5721 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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