IHC of Insulin on an FFPE Pancreas Tissue

IHC of Insulin on an FFPE Pancreas Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Insulin is produced in the beta cells of the Islets of Langerhans in the pancreas. It is a polypeptide hormone that regulates carbohydrate metabolism. Apart from being the primary agent in carbohydrate homeostasis, insulin has effects on fat metabolism and changes the liver’s ability in storing or releasing glucose and processing blood lipids, and in other tissues such as fat and muscle. The amount of insulin in circulation has extremely widespread effects throughout the body. The presence of insulin in the cytoplasm of Islet Tumors is the most reliable indication of functional Insulinomas. Defective insulin storage occurs in Insulinomas; therefore, many sections of the tumor should be stained with both insulin and C-peptide.
Antibody Type Mouse Monoclonal Clone BSB-42
Isotype IgG1/K Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Pancreas
Presentation Insulin is a purified immunoglobulin fraction of rabbit antiserum that is filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 5694 Prediluted Ready-To-Use 3.0 ml
BSB 5695 Prediluted Ready-To-Use 7.0 ml
BSB 5696 Prediluted Ready-To-Use 15.0 ml
BSB 5697 Concentrated 1:250-1:1000 0.1 ml
BSB 5698 Concentrated 1:250-1:1000 0.5 ml
BSB 5699 Concentrated 1:250-1:1000 1.0 ml
BSB 5700 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
Related Products