IHC of Inhibin Alpha on a FFPE Testicular Cancer Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Inhibins are peptide hormones produced by the granulosa cells in female follicles and by Sertoli cells in the male seminiferous tubules. They are selectively expressed by cells of sex-cord stromal derivation, and inhibit the secretion of follitropin by the pituitary gland. Inhibin contains an alpha and beta subunit linked by disulfide bonds. Two forms of inhibin differ in their beta subunits (A or B), while their alpha subunits are identical. Inhibin belongs to the transforming growth factor-beta (TGF-beta) family.

Anti-Inhibin Alpha has demonstrated utility in differentiation between Adrenal Cortical Tumors and Renal Cell Carcinoma. Sex-Cord Stromal Tumors of the Ovary as well as Trophoblastic Tumors also demonstrate cytoplasmic positivity with this antibody.

Antibody Type Rabbit Monoclonal Clone EP378
Isotype IgG Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Testis, Seminoma, Testicular Carcinoma
Presentation Inhibin Alpha is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 3356 Prediluted Ready-To-Use 3.0 ml
BSB 3357 Prediluted Ready-To-Use 7.0 ml
BSB 3358 Prediluted Ready-To-Use 15.0 ml
BSB 3359 Concentrated 1:50-1:200 0.1 ml
BSB 3360 Concentrated 1:50-1:200 0.5 ml
BSB 3361 Concentrated 1:50-1:200 1.0 ml
BSB 3362 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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