IHC of IgA on an FFPE Tonsil Tissue

IHC of IgA on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Immunoglobulin A (IgA) is the main immunoglobulin in mucous secretions, including tears, saliva, and colostrum, as well as respiratory, intestinal, prostatic, and vaginal secretions. It is also found in small amounts in blood. Because it is resistant to degradation by enzymes, secretory IgA provides protection against microbes proliferating in body secretions, especially those of the digestive and respiratory tracts. IgA antibody reacts with surface immunoglobulin IgA alpha chains. It is extremely useful when identifying Acute Leukemias, IgA Myelomas, Plasmacytomas, and B-cell lineage derived Hodgkin’s Lymphomas. However, due to the restricted expression of heavy and light chains in these diseases, demonstration of B-cell Lymphomas is possible with clonal gene-rearrangement studies.
Antibody Type Mouse Monoclonal Clone BSB-39
Isotype IgG1/K Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Tonsil, Lymph Node, Spleen, Kidney, Colon
Presentation IgA is a purified immunoglobulin fraction of rabbit antiserum that is filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 5659 Prediluted Ready-To-Use 3.0 ml
BSB 5660 Prediluted Ready-To-Use 7.0 ml
BSB 5661 Prediluted Ready-To-Use 15.0 ml
BSB 5662 Concentrated 1:250-1:1000 0.1 ml
BSB 5663 Concentrated 1:250-1:1000 0.5 ml
BSB 5664 Concentrated 1:250-1:1000 1.0 ml
BSB 5665 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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