IHC of HER-2 RMab on an FFPE Breast Carcinoma Tissue
|Intended Use||For Analyte Specific Reagent|
|Summary and Explanation||HER2 /ErbB2 is one of four members of the ErbB receptor family of transmembrane
receptor-like tyrosine kinases .The kinase activity of ErbB2 can be activated without
a ligand if it is overexpressed, and by association with other ErbB proteins.
HER2 is overexpressed in 25–30% of all breast cancers, including primary as well
as metastatic breast tumors. HER2 has been widely investigated as a prognostic
|Antibody Type||Rabbit Monoclonal||Clone||EP3|
|Presentation||HER-2 neu is a rabbit monoclonal antibody derived from cell culture supernatant
that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5,
containing BSA and sodium azide as a preservative.
|Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.|