IHC of Helicobacter pylori on an FFPE Infected Stomach Tissue

United States
International
Research Use
Safety Data Sheet

SDS

Control Slides
Intended Use Analyte-Specific Reagent
Summary and Explanation

Helicobacter pylori is a helix-shaped Gram-negative bacterium about 3 μm long with a diameter of about 0.5 μm. It is microaerophilic; that is, it requires oxygen, but at lower concentration than is found in the atmosphere. It contains a hydrogenase which can be used to obtain energy by oxidizing molecular hydrogen (H2) produced by intestinal bacteria. It produces oxidase, catalase, and urease.  H. pylori has four to six lophotrichous flagella; all gastric and enterohepatic Helicobacter species are highly motile owing to flagella. H. pylori’s helical shape (from which the genus name is derived) is thought to have evolved to penetrate the mucoid lining of the stomach. Strains of H. pylori that produce high levels of two proteins, vacuolating toxin A (VacA) and the cytotoxin-associated gene A (CagA), appear to cause greater tissue damage than those that produce lower levels or that lack those genes completely.

Antibody Type Rabbit Monoclonal Clone EP279
Isotype IgG Reactivity Paraffin, Frozen
Localization Cell Wall Control

Helicobacter pylori Infected Stomach Mucosa

Presentation Anti-H. Pylori is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 3279 Prediluted Ready-To-Use 3.0 ml
BSB 3280 Prediluted Ready-To-Use 7.0 ml
BSB 3281 Prediluted Ready-To-Use 15.0 ml
BSB 3282 Concentrated 1:50-1:200 0.1 ml
BSB 3283 Concentrated 1:50-1:200 0.5 ml
BSB 3284 Concentrated 1:50-1:200 1.0 ml
BSB 3285 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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