IHC of Granzyme B on an FFPE Tonsil Tissue

IHC of Granzyme on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Granzymes are exogenous serine proteases that are released by cytoplasmic granules within cytotoxic T-cells and natural killer cells. Their purpose is to induce apoptosis within virus-infected cells, thus destroying them. Anti-Granzyme B antibodies have been useful in diagnosing Natural Killer/T-cell Lymphoma, as well as Anaplastic Large Cell Lymphoma. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin’s Disease.
Antibody Type Rabbit Polyclonal Clone N/A
Isotype N/A Reactivity Paraffin, Frozen
Localization Cytoplasmic (Granular) Control Liver, Testis, Cervix, Tonsil, Lymph Node, Spleen
Presentation Granzyme B is a purified immunoglobulin fraction of rabbit antiserum that is filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 5589 Prediluted Ready-To-Use 3.0 ml
BSB 5590 Prediluted Ready-To-Use 7.0 ml
BSB 5591 Prediluted Ready-To-Use 15.0 ml
BSB 5592 Concentrated 1:25-1:100 0.1 ml
BSB 5593 Concentrated 1:25-1:100 0.5 ml
BSB 5594 Concentrated 1:25-1:100 1.0 ml
BSB 5595 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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