IHC of ERG on an FFPE Prostate Carcinoma Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation ERG belongs to the ETS family that plays important roles in cell development, differentiation, proliferation, apoptosis and tissue remodeling. The aberrant expression of several ETS proteins is involved in tumor development and progression. ERG is linked to normal processes such as mesoderm formation. TMPRSS2-ERG fusion, which occurs on account of translocations and interstitial deletions, is implicated in aggressive forms of prostate cancer.
ERG overexpression is associated with aggressive tumor behavior and patient survival in prostate cancer. ERG antibody labels endothelial cells, lymphocytes, and prostate cancer cells.
Antibody Type Rabbit Monoclonal Clone EP111
Isotype IgG Reactivity Paraffin, Frozen
Localization Nuclear Control Prostate, Colon, Kidney, Fallopian Tube, Tonsil, Myometrium, Skin, Brain, Breast
Presentation ERG is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 6737 Prediluted Ready-To-Use 3.0 ml
BSB 6738 Prediluted Ready-To-Use 7.0 ml
BSB 6739 Prediluted Ready-To-Use 15.0 ml
BSB 6740 Concentrated 1:100-1:500 0.1 ml
BSB 6741 Concentrated 1:100-1:500 0.5 ml
BSB 6742 Concentrated 1:100-1:500 1.0 ml
BSB 6743 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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