IHC of Epstein Barr Virus on an FFPE Hodgkin’s Lymphoma Tissue

United States
International
Research Use
Safety Data Sheet

SDS

Control Slides
Intended Use Analyte Specific Reagent: analytical and performance characteristics are not established
Summary and Explanation

The Epstein-Barr virus (EBV), also called Human Herpesvirus 4 (HHV-4), is a virus of the Herpes family, and is one of the most common viruses in humans. The virus can execute many distinct programs of gene expression, which can be broadly categorized as being lytic cycle or latent cycle. The lytic cycle, or productive infection, results in staged expression of several viral proteins with the ultimate objective of producing infectious virions. The latent cycle (lysogenic) programs are those that do not result in production of virions. A very limited, distinct set of viral proteins are produced during latent cycle infection. These include Epstein-Barr nuclear antigens EBNA-1, EBNA-2, EBNA-3A, EBNA-3B, EBNA-3C, EBNA-leader protein (EBNA-LP), latent membrane proteins LMP-1, LMP-2A and LMP-2B and the Epstein-Barr encoded RNAs (EBERs). In addition, EBV codes for at least twenty microRNAs which are expressed in latently infected cells.

Antibody Type Mouse Monoclonal Clone CS1-4
Isotype IgG1 Reactivity Paraffin, Frozen
Localization Cytoplasmic Control EBV Infected Tissue, Hodgkin’s Lymphoma
Presentation Uroplakin III is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 5484 Prediluted Ready-To-Use 3.0 ml
BSB 5485 Prediluted Ready-To-Use 7.0 ml
BSB 5486 Prediluted Ready-To-Use 15.0 ml
BSB 5487 Concentrated 1:25-1:100 0.1 ml
BSB 5488 Concentrated 1:25-1:100 0.5 ml
BSB 5489 Concentrated 1:25-1:100 1.0 ml
BSB 5490 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
Related Products