IHC of cytokeratin 7 on an FFPE Lung Adenocarcinoma Tissue

Specification Sheets
Safety Data Sheet


Intended Use For In Vitro Diagnostic Use
Summary and Explanation Cytokeratin 7 (CK7) reacts with proteins that are found in most ductal, glandular and transitional epithelium of the urinary tract and bile duct epithelial cells. CK7 distinguishes between lung and breast epithelium that stain positive, and colon and prostate epithelial cells that are negative. This antibody also reacts with many benign and malignant epithelial lesions (e.g., Adenocarcinomas of the ovary, breast and lung). Further, in frozen sections, the antibody has been shown to label the rete epithelium in the testis, epididymis epithelium, and the surface epithelium of the stomach and duodenum. Transitional-cell Carcinomas are positive and Prostate Cancers are negative. This antibody does not recognize intermediate filament proteins, nor does it recognize non-epithelial tissues such as blood vessels, connective tissue, etc.
Antibody Type Mouse Monoclonal Clone OV-TL 12/30
Isotype IgG1/K Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Salivary Gland, Placenta, Breast, Thyroid, Cervix, Pancreas, Fallopian Tube, Transitional Cell Carcinoma, Lung, Adenocarcinoma
Presentation Cytokeratin 7 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No. Antibody Type Dilution Volume/QTY
BSB 5407 Prediluted Ready-To-Use 3.0 ml
BSB 5408 Prediluted Ready-To-Use 7.0 ml
BSB 5409 Prediluted Ready-To-Use 15.0 ml
BSB 5410 Concentrated 1:100-1:500 0.1 ml
BSB 5411 Concentrated 1:100-1:500 0.5 ml
BSB 5412 Concentrated 1:100-1:500 1.0 ml
BSB 5413 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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