IHC of Cytokeratin 15 on an FFPE Skin Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Cytokeratin 15 (CK15) is involved in the development of stratified epithelia from one-layered polar epithelia and continues to be expressed in several adult epithelial tissues. It labels the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. Although CK15 in normal hair follicles was virtually absent from hair bulbs, it was expressed by a subset of keratinocytes in the outer root sheath. In human conjunctival epithelium, strong expression of CK15 is observed in basal cells, whereas Cytokeratin 19 is expressed in both basal and suprabasal layers.
CK15 may be used to differentiate primary from metastatic skin cancer. It may be a useful stem cell marker for hair follicle and breast epithelium.
Antibody Type Rabbit Monoclonal Clone EP14
Isotype IgG Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Skin, Cervical Carcinoma
Presentation CK15 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 6688 Prediluted Ready-To-Use 3.0 ml
BSB 6689 Prediluted Ready-To-Use 7.0 ml
BSB 6690 Prediluted Ready-To-Use 15.0 ml
BSB 6691 Concentrated 1:25-1:100 0.1 ml
BSB 6692 Concentrated 1:25-1:100 0.5 ml
BSB 6693 Concentrated 1:25-1:100 1.0 ml
BSB 6694 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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