IHC of Claudin-1 on an FFPE Skin Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Claudin 1 is an integral membrane protein and a component of tight junction strands. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are composed of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet.
Claudin-1 stains membraines of cells and is found in nearly all carcinomas, with stains much stronger in carcinoma cells than in normal tissue cells.
Antibody Type Rabbit Polyclonal Clone Polyclonal
Isotype IgG Reactivity Paraffin, Frozen
Localization Membranous, Cytoplasmic Control Skin, Small intestine. Perineurioma, Neurofibroma, colon Carcinoma
Presentation Claudin 1 is a Rabbit Polyclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 6562 Prediluted Ready-To-Use 3.0 ml
BSB 6563 Prediluted Ready-To-Use 7.0 ml
BSB 6564 Prediluted Ready-To-Use 15.0 ml
BSB 6565 Concentrated 1:50-1:200 0.1 ml
BSB 6566 Concentrated 1:50-1:200 0.5 ml
BSB 6567 Concentrated 1:50-1:200 1.0 ml
BSB 6568 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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