IHC of Cytokeratin 8 on an FFPE Colon Tissue
|Intended Use||For In Vitro Diagnostic Use|
|Summary and Explanation||Cytokeratin 8, also known as type II cytoskeletal 8, is a protein that is often paired with Cytokeratin 18. They are perhaps the most commonly found products of the intermediate filament gene family, and are expressed in single-layer epithelial tissues of the body. Cytokeratin 8 is an intermediate filament protein produced early in embryogenesis.
Anti-Cytokeratin 8 can be used to detect Adenocarcinomas with simple epithelium origin. It can be used to distinguish between Duct (peripheral staining) from Lobular (perinuclear staining) Breast Carcinoma.
|Antibody Type||Rabbit Monoclonal||Clone||EP17|
|Localization||Cytoplasmic||Control||Colon, Prostate, Kidney, Liver, Colon Carcinoma|
|Presentation||CK8 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.|
|Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.|