IHC of cytokeratin 7 on an FFPE Lung Carcinoma Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Cytokeratin 7 (CK7) reacts with proteins that are found in most ductal, glandular and transitional epithelium of the urinary tract and bile duct epithelial cells. CK7 distinguishes between lung and breast epithelium that stain positive, and colon and prostate epithelial cells that are negative.
This antibody also reacts with many benign and malignant epithelial lesions (e.g., Adenocarcinomas of the ovary, breast and lung). Further, in frozen sections, the antibody has been shown to label the rete epithelium in the testis, epididymis epithelium, and the surface epithelium of the stomach and duodenum. Transitional-cell Carcinomas are positive and Prostate Cancers are negative. This antibody does not recognize intermediate filament proteins, nor does it recognize non-epithelial tissues such as blood vessels, connective tissue, etc.
Antibody Type Rabbit Monoclonal Clone EP16
Isotype IgG Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Salivary Gland, Placenta, Breast, Thyroid, Cervix, Lung Adenocarcinoma
Presentation CK7 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 6646 Prediluted Ready-To-Use 3.0 ml
BSB 6647 Prediluted Ready-To-Use 7.0 ml
BSB 6648 Prediluted Ready-To-Use 15.0 ml
BSB 6649 Concentrated 1:50-1:200 0.1 ml
BSB 6650 Concentrated 1:50-1:200 0.5 ml
BSB 6651 Concentrated 1:50-1:200 1.0 ml
BSB 6652 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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