IHC of Cytokeratin 6 on an FFPE Cervical Cancer Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Cytokeratin 6 is a type II cytokeratin known for its strong induction in stratified epithelia that features an enhanced cell proliferation rate or abnormal differentiation during wound healing in several diseases (such as psoriasis, actinic keratosis) and in cancer. It can be found on stratified epithelia including oral mucosa, esophagus, basal layer of epidermis, the outer root sheath of hair follicles, and in glandular epithelia.
Together, CK 5 & 6 can be used to differentiate Mesothelioma (positive) from Lung Carcinoma (negative) or metastatic carcinoma (negative), and can also be used to distinguish between Ductal Hyperplasia of the breast (positive) from Solid Papillary DCIS (negative).
Antibody Type Rabbit Monoclonal Clone EP67
Isotype IgG Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Oral Mucosa, Esophagus, Skin, Glandular Epithelia
Presentation CK6 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 6639 Prediluted Ready-To-Use 3.0 ml
BSB 6640 Prediluted Ready-To-Use 7.0 ml
BSB 6641 Prediluted Ready-To-Use 15.0 ml
BSB 6642 Concentrated 1:25-1:100 0.1 ml
BSB 6643 Concentrated 1:25-1:100 0.5 ml
BSB 6644 Concentrated 1:25-1:100 1.0 ml
BSB 6645 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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