IHC of CD57 on an FFPE Tonsil Tissue

IHC of CD57 on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation CD57 (NK-1) recognizes an oligosaccharide (MW 100-110 kDa) antigenic determinant on myeloid cells and on a variety of polypeptides, lipids and chondroitan sulfate proteoglycans. This surface antigen is associated with myelin-associated glycoprotein (MAG). The CD57 antigen is present on 15-20% of normal peripheral blood mononuclear cells. It is expressed on a subset of natural killer cells (60%) and on a subset of T-lymphocytes. This carbohydrate is also present on N-CAM in the nervous system. Follicular Center-cell Lymphomas often contain many NK cells within the neoplastic follicles. NK-1 reportedly also reacts with a variety of cell types in non-lymphoid tissues. NK-1 stains neuroendocrine cells and their tumors, including Carcinoid Tumor and Medulloblastomas. NK-1 also reacts with a variety of cell types in non-lymphoid tissues, including Neurofibroma, Ganglioneuroma, and Prostate Carcinoma.
Antibody Type Mouse Monoclonal Clone BSB-10 (CD57/B8)
Isotype IgM/K Reactivity Paraffin, Frozen
Localization Membranous Control Tonsil, Lymph Node
Presentation CD57 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 5274 Prediluted Ready-To-Use 3.0 ml
BSB 5275 Prediluted Ready-To-Use 7.0 ml
BSB 5276 Prediluted Ready-To-Use 15.0 ml
BSB 5277 Concentrated 1:100-1:500 0.1 ml
BSB 5278 Concentrated 1:100-1:500 0.5 ml
BSB 5279 Concentrated 1:100-1:500 1.0 ml
BSB 5280 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
Related Products