IHC of CD45RA on an FFPE Tonsil Tissue

IHC of CD45RA on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation CD45 is a complex molecule and is comprised of different glycoproteins ranging from 180-240 kDa. Expression of CD45 is found on all hemopoietic cells. Detection of the different isoforms can distinguish between different cell forms (e.g., naive T-cells and memory T-cells). CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells. CD45RA antibody reacts with mature, non-activated T and B-cells. CD45RA is also reactive with medullary thymocytes, mantle-zone lymphocytes in follicles of lymph nodes, spleen and lymphocytes of the paracortex. CD45RA shows no reactivity with cortical thymocytes, immature T-cells or activated B-cells in germinal centers.
Antibody Type Mouse Monoclonal Clone 4KB5
Isotype IgG1/K Reactivity Paraffin, Frozen
Localization Membranous Control Tonsil, Lymph Node
Presentation CD45RA is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 5253 Tinto Prediluted Ready-To-Use 3.0 ml
BSB 5254 Tinto Prediluted Ready-To-Use 7.0 ml
BSB 5255 Tinto Prediluted Ready-To-Use 15.0 ml
BSB 5256 Concentrated 1:25-1:100 0.1 ml
BSB 5257 Concentrated 1:25-1:100 0.5 ml
BSB 5258 Concentrated 1:25-1:100 1.0 ml
BSB 5259 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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