IHC of CD41/Integrin alpha lib on a FFPE Spleen Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation ITGA2B encodes CD41, or integrin alpha IIb. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain IIb undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibrinogen receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface medicated signalling.
CD41 expression has been found on platelets, megakaryocyes, and immature hematopoietic progenitors.
Antibody Type Rabbit Monoclonal Clone EP178
Isotype IgG Reactivity Paraffin, Frozen
Localization Membranous, Cytoplasmic Control Bone Marrow, Spleen
Presentation CD41 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 6506 Prediluted Ready-To-Use 3.0 ml
BSB 6507 Prediluted Ready-To-Use 7.0 ml
BSB 6508 Prediluted Ready-To-Use 15.0 ml
BSB 6509 Concentrated 1:25-1:100 0.1 ml
BSB 6510 Concentrated 1:25-1:100 0.5 ml
BSB 6511 Concentrated 1:25-1:100 1.0 ml
BSB 6512 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
Specification Sheets
Safety Data Sheet

SDS

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