IHC of CD4 on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation CD4 is a glycoprotein expressed on the surface of T-helper cells, regulatory T-cells, monocytes, macrophages, and dendritic cells. On T-cells, CD4 is the co-receptor for the T-cell receptor (TCR). It amplifies the signal gener-ated by the TCR by recruiting the tyrosine kinase that is essential for activating many molecules involved in the signaling cascade of an activated T-cell. CD4 antigen is involved in the recognition of Type II Major Histocompatability Complex antigens (MHC-II). CD4 is also the receptor for Human Immunodeficiency Virus (HIV). It is present on most T-helper cells and normal thymocytes.
Antibody Type Rabbit Monoclonal Clone RBT-CD4
Isotype IgG Reactivity Paraffin, Frozen
Localization Membranous Control Tonsil, Lymph Node
Presentation CD4 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 5148 Prediluted Ready-To-Use 3.0 ml
BSB 5149 Prediluted Ready-To-Use 7.0 ml
BSB 5150 Prediluted Ready-To-Use 15.0 ml
BSB 5151 Concentrated 1:25-1:100 0.1 ml
BSB 5152 Concentrated 1:25-1:100 0.5 ml
BSB 5153 Concentrated 1:25-1:100 1.0 ml
BSB 5154 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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