IHC of CD38 on an FFPE Tonsil Tissue

IHC of CD38 on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationCD38 is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B and natural killer cells. It is a marker of cell activation. The CD38 protein has been linked to HIV infection, Leukemias, Myelomas, solid tumors, Type II Diabetes Mellitus and bone metabolism, as well as some genetically-determined conditions. It has also been used as a prognostic marker in Leukemia. CD38 is highly expressed on thymocytes. It is also expressed by early cells of B and T lineages, NK cells, plasma cells, monocytes and macrophages, and may be detected on cells from Multiple Myeloma, ALL (B and T) and some AML.
Monoclonal antibodies to CD38 have been shown to be useful in subtyping of Lymphomas and Leukemias, inhibition of B-lymphopoiesis, detection of plasma cells, protection of B-cells from apoptosis, and as a marker for activated B and T-cell proliferation.
Antibody TypeRabbit MonoclonalCloneEP135
IsotypeIgGReactivityParaffin, Frozen
LocalizationMembranousControlTonsil, Lymph Node, Breast
PresentationCD38 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 6499PredilutedReady-To-Use3.0 ml
BSB 6500PredilutedReady-To-Use7.0 ml
BSB 6501PredilutedReady-To-Use15.0 ml
BSB 6502Concentrated1:25-1:1000.1 ml
BSB 6503Concentrated1:25-1:1000.5 ml
BSB 6504Concentrated1:25-1:1001.0 ml
BSB 6505Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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