IHC of CD35 on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation CD35 (erythrocyte complement receptor 1 or CR1, also known as C3b/C4b receptor and immune adherence receptor) serves as the main system for processing and clearance of complement- opsonized immune complexes. The number of CR1 molecules decreases with aging of erythrocytes in normal individuals and is also decreased in pathological conditions such as Systemic Lupus Erythematosus (SLE), HIV infection, some Hemolytic Anemias and other conditions featuring immune complexes. Anti-CD35 is considered a mature B-cell marker, which labels follicular dendritic reticulum cells and tumors derived from such cells such as Follicular Dendritic Cell Tumor/Sarcoma. CD35 antigen is found in erythrocytes, B-cells, and a subset of T-cells, monocytes, as well as in eosinophils and neutrophils.
Antibody Type Mouse Monoclonal Clone RLB25
Isotype IgG2b Reactivity Paraffin, Frozen
Localization Membranous Control Tonsil, Lymph Node
Presentation CD35 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 5232 Prediluted Ready-To-Use 3.0 ml
BSB 5233 Prediluted Ready-To-Use 7.0 ml
BSB 5234 Prediluted Ready-To-Use 15.0 ml
BSB 5235 Concentrated 1:25-1:100 0.1 ml
BSB 5236 Concentrated 1:25-1:100 0.5 ml
BSB 5237 Concentrated 1:25-1:100 1.0 ml
BSB 5238 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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