IHC of CD35 on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationCD35 (erythrocyte complement receptor 1 or CR1, also known as C3b/C4b receptor and immune adherence receptor) serves as the main system for processing and clearance of complement- opsonized immune complexes. The number of CR1 molecules decreases with aging of erythrocytes in normal individuals and is also decreased in pathological conditions such as Systemic Lupus Erythematosus (SLE), HIV infection, some Hemolytic Anemias and other conditions featuring immune complexes. Anti-CD35 is considered a mature B-cell marker, which labels follicular dendritic reticulum cells and tumors derived from such cells such as Follicular Dendritic Cell Tumor/Sarcoma. CD35 antigen is found in erythrocytes, B-cells, and a subset of T-cells, monocytes, as well as in eosinophils and neutrophils.
Antibody TypeMouse MonoclonalCloneRLB25
IsotypeIgG2bReactivityParaffin, Frozen
LocalizationMembranousControlTonsil, Lymph Node
PresentationCD35 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5232PredilutedReady-To-Use3.0 ml
BSB 5233PredilutedReady-To-Use7.0 ml
BSB 5234PredilutedReady-To-Use15.0 ml
BSB 5235Concentrated1:25-1:1000.1 ml
BSB 5236Concentrated1:25-1:1000.5 ml
BSB 5237Concentrated1:25-1:1001.0 ml
BSB 5238Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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