IHC of CD31 on an FFPE Tonsol Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation CD31 is also called PECAM-1 for platelet endothelial cell-adhesion molecule. It plays a key role in removing aged neutrophils from the body. CD-31 is normally found on stem cells, endothelial cells, platelets, macrophages and Kupffer cells, granulocytes, T/NK cells, lymphocytes, megakaryocytes, fibroblasts, osteoclasts and neutrophils. CD-31 is also expressed in certain tumors, including Epithelioid Hemangioendothelioma, Epithelioid Sarcoma-like Hemangioendothelioma, other vascular tumors, Histiocytic malignancies, and Plasmacytomas. It is rarely found in some sarcomas and carcinomas. CD-31 and macrophages play a key role in tissue regeneration. CD31 is widely used to identify the vascular origin of neoplasms, as it is a highly specific and sensitive marker for vascular endothelial cells.
Antibody Type Mouse Monoclonal Clone 1A10
Isotype IgG1/K Reactivity Paraffin, Frozen
Localization Cytoplasmic, Membranous Control Tonsil, Placenta, Appendix, Spleen, Kidney
Presentation CD31 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 5218 Prediluted Ready-To-Use 3.0 ml
BSB 5219 Prediluted Ready-To-Use 7.0 ml
BSB 5220 Prediluted Ready-To-Use 15.0 ml
BSB 5221 Concentrated 1:50-1:200 0.1 ml
BSB 5222 Concentrated 1:50-1:200 0.5 ml
BSB 5223 Concentrated 1:50-1:200 1.0 ml
BSB 5224 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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