IHC of CD25 on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation CD25 is the alpha chain of the IL-2 receptor. It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes that associates with CD122 to form a heterodimer that can act as a high-affinity receptor for IL-2. Studies have shown that a large proportion of resting memory T cells constitutively express CD25. CD25 is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. Its soluble form, called sIL-2R may be elevated in these diseases and is occasionally used to track disease progression. CD25 is also utilized in cases of mastocytosis
Antibody Type Rabbit Monoclonal Clone RBT-CD25
Isotype IgG Reactivity Paraffin, Frozen
Localization Cytoplasmic, Membranous Control Tonsil, Small Bowel, Spleen, Mastocytosis,Hodgkin’s Lymphoma
Presentation CD25 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 2454 Prediluted Ready-To-Use 3.0 ml
BSB 2455 Prediluted Ready-To-Use 7.0 ml
BSB 2456 Prediluted Ready-To-Use 15.0 ml
BSB 2457 Concentrated 1:10-1:50 0.1 ml
BSB 2458 Concentrated 1:10-1:50 0.5 ml
BSB 2459 Concentrated 1:10-1:50 1.0 ml
BSB 2460 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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