IHC of CD23 on an FFPE Lymphoma Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation CD23, also known as Fc epsilon RII, is the “low affinity” receptor for IgE, an antibody isotype involved in allergy and (arguably) resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B-cells, activated macrophages, eosinophils, follicular dendritic cells and platelets.
This is a B-cell antibody that is useful for differentiating between B-CLL and B-SLL’s that are CD23-positive from Mantle-cell Lymphomas and Small-Cleaved Lymphomas that are CD23- negative. This antibody reacts with the antigen that is found on a subpopulation of peripheral blood cells, B-lymphocytes and on EBV-transformed B-lymphoblastoid cell lines.
Antibody Type Rabbit Monoclonal Clone EP75
Isotype IgG Reactivity Paraffin, Frozen
Localization Membranous Control Tonsil, Lymph Node
Presentation CD23 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 6471 Prediluted Ready-To-Use 3.0 ml
BSB 6472 Prediluted Ready-To-Use 7.0 ml
BSB 6473 Prediluted Ready-To-Use 15.0 ml
BSB 6474 Concentrated 1:50-1:200 0.1 ml
BSB 6475 Concentrated 1:50-1:200 0.5 ml
BSB 6476 Concentrated 1:50-1:200 1.0 ml
BSB 6477 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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