IHC of CD20 on an FFPE Colon Tissue

IHC of CD20 on an FFPE Colon Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation CD20 is a transmembrane, non-glycosylated protein expressed on B-cell precursors and mature B-cells, but lost following differentiation into plasma cells. This antibody does not cross-react with non-hematopoietic neoplasms. CD20 (B-cell Pan) reacts with a membrane antigen present in B-cells. This antibody strongly recognizes Reed-Sternberg cells predominant in Hodgkin’s disease. Since no staining of histiocytes or plasma cells has been observed and CD20 has not been detected in T-cell malignancies, it is a very strong marker of B-cell Lymphomas. B-cell Panmarker recognizes a formalin-resistant intracytoplasmic antigen.
Antibody Type Mouse Monoclonal Clone L26
Isotype IgG2a/K Reactivity Paraffin, Frozen
Localization Membranous Control Tonsil, Lymph Node
Presentation CD20 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 5190 Prediluted Ready-To-Use 3.0 ml
BSB 5191 Prediluted Ready-To-Use 7.0 ml
BSB 5192 Prediluted Ready-To-Use 15.0 ml
BSB 5193 Concentrated 1:250-1:1000 0.1 ml
BSB 5194 Concentrated 1:250-1:1000 0.5 ml
BSB 5195 Concentrated 1:250-1:1000 1.0 ml
BSB 5196 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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