CD15-MMab

IHC of CD15 on an FFPE Hodgkin’s Lymphoma Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation CD15 is a phosphatidylinositol-anchored transmembrane protein found on neutrophils and which may be involved in phagocytosis. It is expressed in patients with Hodgkin’s Disease, some B-cell Chronic Lymphocytic Leukemias, Acute Lymphoblastic Leukemias, and most Acute Non-Lymphocytic Leukemias. It is also called Lewis x. A positive reaction for CD15 combined with a negative reaction for CD45 and other B and T-lineage markers provides support for Reed-Sternberg cells found in Hodgkin’s disease. Also, this antibody does not detect Mesotheliomas, making it a more frequently used antibody to distinguish Epithelial Mesothelioma from Adenocarcinoma.
Antibody Type Mouse Monoclonal Clone BSB-119
Isotype IgM Reactivity Paraffin, Frozen
Localization Cytoplasmic, Membranous Control Tonsil, Lymph Node, Hodgkin’s Lymphoma
Presentation CD15 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 5183 Prediluted Ready-To-Use 3.0 ml
BSB 5184 Prediluted Ready-To-Use 7.0 ml
BSB 5185 Prediluted Ready-To-Use 15.0 ml
BSB 5186 Concentrated 1:50-1:200 0.1 ml
BSB 5187 Concentrated 1:50-1:200 0.5 ml
BSB 5188 Concentrated 1:50-1:200 1.0 ml
BSB 5189 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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