CD13-MMab

IHC of CD13 on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation CD13 (also known as aminopeptidase-N) is expressed on the majority of peripheral blood monocytes and granulocytes. It is also expressed by the majority of acute myeloid leukemias, chronic myeloid leukemias in myeloid blast crisis, a smaller percentage of lymphoid leukemias and myeloid cell lines. CD13 is absent from normal lymphocytes, platelets and erythrocytes. CD13 is also present on fibroblasts, endothelial cells, epithelial cells from renal proximal tubules and intestinal brush border, bone marrow stromal cells, osteo-clasts, and cells forming bile canaliculi. Anti-Human CD13 recognizes the human CD13 antigen expressed on the majority of peripheral blood monocytes and granulocytes and on endothelial cells. CD13 plays a role in biologically active peptide metabolism, in the control of growth and diff erentiation, in phagocytosis and in bactericidal/tumoricidal activities. CD13 also serves as a receptor for human coronaviruses (HCV)
Antibody Type Mouse Monoclonal Clone 38C12
Isotype IgG1 Reactivity Paraffin, Frozen
Localization Cytoplasmic, Membranous Control Spleen, Tonsil, Prostate, Liver
Presentation CD13 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 6324 Prediluted Ready-To-Use 3.0 ml
BSB 6325 Prediluted Ready-To-Use 7.0 ml
BSB 6326 Prediluted Ready-To-Use 15.0 ml
BSB 6327 Concentrated 1:25-1:50 0.1 ml
BSB 6328 Concentrated 1:25-1:50 0.5 ml
BSB 6329 Concentrated 1:25-1:50 1.0 ml
BSB 6330 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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