CD11c

IHC of CD11cĀ on an FFPE SpleenĀ Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation CD11c (1TGAX) is a member of the leukointegrin family and shares the same beta subunit with other members of the leukocyte adhesion molecule family, which include CD11a (LFA-1), CD11b (MAC-1), and CD11d (ITGAD), but has a unique alpha chain. CD11c is a type I transmembrane protien found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst.
CD11c is expressed in Hairy Cell leukemias, Acute Nonlymphocytic Leukemias, and some B-cell Chronic Lymphocytic Leukemias.
Antibody Type Rabbit Monoclonal Clone EP157
Isotype IgG Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Bone Marrow, Spleen, Tonsil, Colon, Hairy Cell
Leukemia
Presentation Cd11c is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 6443 Prediluted Ready-To-Use 3.0 ml
BSB 6444 Prediluted Ready-To-Use 7.0 ml
BSB 6445 Prediluted Ready-To-Use 15.0 ml
BSB 6446 Concentrated 1:25-1:50 0.1 ml
BSB 6447 Concentrated 1:25-1:50 0.5 ml
BSB 6448 Concentrated 1:25-1:50 1.0 ml
BSB 6449 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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