|Intended Use||For In Vitro Diagnostic Use|
|Summary and Explanation||CD138/Syndecan-1 is a transmembrane heparin-sulphate proteoglycan consisting of one core protein and five glycosaminoglycans. CD138 is suspected to play a role in cell adhesion. It is expressed on the surface of pre B-cells and plasma cells but is absent from mature B-cells.
Anti-CD138/syndecan-1 is a useful marker for labeling normal and neoplastic plasma cells and Plasmacytoid Lymphomas. It is a selective marker for B-cell Lymphoblastic Leukemia and Lymphoplasmocytoid Leukemia. It is lost from the apoptotic myeloma cells, and thus, is a useful marker for viable Myeloma cells. Various forms of Hodgkin’s Disease have also shown positive staining with this antibody.
|Antibody Type||Rabbit Monoclonal||Clone||EP201|
|Localization||Membranous||Control||Tonsil, Liver, Kidney, Breast, Lymph Node, Cervix, Plasmacytoma, Adrenal, Skin, Colon|
|Presentation||CD138 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.|
|Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.|