Calcitonin RMab

IHC of Calcitonin on an FFPE Thyroid Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Calcitonin is a 32-amino acid polypeptide hormone that is produced in humans primarily by C-cells located in the thyroid, and in many other animals in the ultimobranchial gland. It acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH). It has been found in fish, reptiles, birds, and mammals. Its importance in humans has not been as well established as in other animals.
Immunohistochemical staining with Calcitonin antibody has proven to be an effective way of demonstrating the existence of Calcitonin-producing cells in the thyroid. C-cell Hyperplasia and Medullary Thyroid Carcinomas stain positive for Calcitonin. Studies of Calcitonin have resulted in the identification of a wide spectrum of C-cell proliferative abnormalities.
Antibody Type Rabbit Monoclonal Clone EP92
Isotype IgG Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Thyroid, Thyroid Medullary Carcinoma
Presentation Calcitonin is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 6408 Prediluted Ready-To-Use 3.0 ml
BSB 6409 Prediluted Ready-To-Use 7.0 ml
BSB 6410 Prediluted Ready-To-Use 15.0 ml
BSB 6411 Concentrated 1:100-1:500 0.1 ml
BSB 6412 Concentrated 1:100-1:500 0.5 ml
BSB 6413 Concentrated 1:100-1:500 1.0 ml
BSB 6414 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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