Cadherin-6

IHC of Cadherin-6 on an FFPE Kidney Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Cadherin-6 is a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. It is a type I cadherin and may play a role in kidney development as well as endometrium and placenta formation.
Cadherin-6 is highly expressed in kidney and the central nervous system. It has been found to be related to fetal kidney development and has been identified as a major cadherin in renal proximal tubules where conventional renal cell carcinoma originates. The expression of Cadherin-6 is associated with tumor progression in renal cell carcinoma.
Antibody Type Rabbit Monoclonal Clone EP217
Isotype IgG Reactivity Paraffin, Frozen
Localization Membranous Control Kidney, Renal Cell Carcinoma
Presentation Cadherin-6 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 2391 Prediluted Ready-To-Use 3.0 ml
BSB 2392 Prediluted Ready-To-Use 7.0 ml
BSB 2393 Prediluted Ready-To-Use 15.0 ml
BSB 2394 Concentrated 1:25-1:100 0.1 ml
BSB 2395 Concentrated 1:25-1:100 0.5 ml
BSB 2396 Concentrated 1:25-1:100 1.0 ml
BSB 2396 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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