IHC of CA-125 on an FFPE Ovarian Carcinoma Tissue
|Intended Use||For In Vitro Diagnostic Use|
|Summary and Explanation||CA-125 reacts with malignant ovarian epithelial cells. CA-125 also reacts with antigens in Seminal Vesicle Carcinoma and Anaplastic Lymphoma.
In adult tissues, CA-125 is found in epithelial cells of Fallopian tube, endometrium and endocervix, pancreas, colon, gall bladder, stomach, kidney, apocrine sweat gland, and mammary gland. It is also found in mesothe- lial cell lining of pleura, pericardium and peritoneum. It is found in ovarian tumors of serous, endometrioid or clear-cell types and Adenocarcinomas of Mullerian type.
|Antibody Type||Rabbit Monoclonal||Clone||EP48|
|Localization||Membranous, Cytoplasmic||Control||Colon, Pancreas, Epitheliod Mesothelioma, Ovarian Carcinoma|
|Presentation||CA-125 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.|
|Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.|