IHC of Bcl-X on an FFPE Hodgkin’s Lymphoma Tissue

Specification Sheets
Safety Data Sheet


Intended Use For In Vitro Diagnostic Use
Summary and Explanation bcl-X, or bcl-2-like 1 protein, a member of the bcl-2 protein family, inhibits cell death, or apoptosis and func-tions as a regulator of apoptosis. bcl-X has two isoforms: bcl-XL (Long), a 241-amino acid protein; and bcl-XS (Short), a 178-amino acid protein lacking a 63-amino acid domain that is well conserved among members of the bcl-2 family. bcl-X is typically present in the cytosol in association with the mitochondrial membrane. bcl-XL forms heterodimers with various proteins, including Bax, Bak and bcl-2. It has been found that heterodimerization with Bax does not seem to be required for anti-apoptotic activity.
Antibody Type Rabbit Monoclonal Clone EP94
Isotype IgG Reactivity Paraffin, Frozen
Localization Cytoplasmic and Cell/Nuclear Membrane Control Hodgkin’s Lymphoma, Kidney, Tonsil, Cervix
Presentation Bcl-X is a purified immunoglobulin fraction of rabbit antiserum that is filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No. Antibody Type Dilution Volume/QTY
BSB 6085 Prediluted Ready-To-Use 3.0 ml
BSB 6086 Prediluted Ready-To-Use 7.0 ml
BSB 6087 Prediluted Ready-To-Use 15.0 ml
BSB 6088 Concentrated 1:250-1:1000 0.1 ml
BSB 6089 Concentrated 1:250-1:1000 0.5 ml
BSB 6090 Concentrated 1:250-1:1000 1.0 ml
BSB 6091 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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