IHC of AFP on an FFPE Fetal Liver Tissue

Specification Sheets
Safety Data Sheet


Intended Use For In Vitro Diagnostic Use
Summary and Explanation Alpha-fetoprotein (AFP) is a protein which in humans is encoded by the AFP gene. This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. This protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem on chromosome 4. Positive staining with this antibody is seen in hepatocytes of fetal liver and hepatoma. Since only traces of AFP are found in adult serum, elevated levels suggest either a benign or malignant lesion of the liver, a Yolk-Sac Carcinoma, or one of a few other tumors. In conjunction with elevated serum levels, AFP has been immunohistochemically demonstrated in Yolk-Sac Carcinomas in gonadal and extragonadal sites of hepatic malignancies and a few other neoplasms.
Antibody Type Mouse Monoclonal Clone BSB-23
Isotype IgG2a/K Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Fetal Liver, Hepatocellular Carcinoma
Presentation Alpha-Fetoprotein is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No. Antibody Type Dilution Volume/QTY
BSB 5050 Prediluted Ready-To-Use 3.0 ml
BSB 5051 Prediluted Ready-To-Use 7.0 ml
BSB 5052 Prediluted Ready-To-Use 15.0 ml
BSB 5053 Concentrated 1:100-1:500 0.1 ml
BSB 5054 Concentrated 1:100-1:500 0.5 ml
BSB 5055 Concentrated 1:100-1:500 1.0 ml
BSB 5056 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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