IHC of Albumin on a FFPE Lupus Erythmatosus Tissue

IF of Albumin on a FFPE Kidney Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use.

This antibody is intended for use in Immunohistochemical (IHC) and Immunofluorescence (IF) applications on formalin-fixed paraffin-embedded tissues (FFPE), frozen tissue sections and cell preparations. Interpretation of results should be performed by a qualified medical professional.

Summary and Explanation The albumins are a family of globular proteins, the most common of which are the serum albumins. Albumins are commonly found in blood plasma and differ from other blood proteins in that they are not glycosylated. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Mutations in this gene on chromosome 4 result in various anomalous proteins.

Low albumin (hypoalbuminemia) may be caused by liver disease, nephrotic syndrome, burns, protein-losing enteropathy, malabsorption, malnutrition, late pregnancy, artefact, genetic variations and malignancy. High albumin (hyperalbuminemia) is almost always caused by dehydration. In some cases of retinol (Vitamin A) deficiency, the albumin level can be elevated to high-normal values.

It has been reported in systemic lupus erythematosus (SLE) patients an increased prevalence of IgG autoantibodies against human serum albumin (anti-HSA IgG) that are associated with SLE disease activity.

Antibody Type Rabbit Polyclonal Clone Polyclonal
Isotype IgG Reactivity Paraffin, Frozen
Localization Cytoplasmic, Membranous Control Salivary Gland, Kidney, Tonsil, Lupus Erythematosus
Presentation Albumin is a purified immunoglobulin fraction of rabbit antiserum that is filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 3012 Prediluted Ready-To-Use* 3.0 ml
BSB 3013 Prediluted Ready-To-Use* 7.0 ml
BSB 3014 Prediluted Ready-To-Use* 15.0 ml
BSB 3015 Concentrated 1:100 / 1:40 0.1 ml
BSB 3016 Concentrated 1:100 / 1:40 0.5 ml
BSB 3017 Concentrated 1:100 / 1:40 1.0 ml
BSB 3018 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

*Ready-to-Use, for IHC only!